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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTBK1 All Species: 9.39
Human Site: S1175 Identified Species: 34.44
UniProt: Q5TCY1 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TCY1 NP_115927.1 1321 142737 S1175 V A A Q Q P A S R S H G A A P
Chimpanzee Pan troglodytes XP_001155217 1244 137355 Y1095 V E A R L R R Y K V L G S S N
Rhesus Macaque Macaca mulatta XP_001088342 1347 145334 S1201 A A A Q Q L P S K S H G A A P
Dog Lupus familis XP_544644 1335 147975 Y1186 V E A R L R R Y K V L G S S N
Cat Felis silvestris
Mouse Mus musculus Q6PCN3 1308 141595 G1166 V E G Q Q L P G R P H G A A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514783 557 61177 P441 P E T K R A R P S G G V S S A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787864 2273 252079 T1614 P E V S E C A T R W Q E P S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 95.8 35.9 N.A. 89.8 N.A. N.A. 33.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.1
Protein Similarity: 100 48.1 96.1 48.6 N.A. 91.9 N.A. N.A. 36.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 38.2
P-Site Identity: 100 20 73.3 20 N.A. 53.3 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 46.6 80 46.6 N.A. 53.3 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 29 58 0 0 15 29 0 0 0 0 0 43 43 15 % A
% Cys: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 72 0 0 15 0 0 0 0 0 0 15 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 15 0 15 15 72 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 15 0 0 0 0 43 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 29 29 0 0 0 0 29 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % N
% Pro: 29 0 0 0 0 15 29 15 0 15 0 0 15 0 29 % P
% Gln: 0 0 0 43 43 0 0 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 29 15 29 43 0 43 0 0 0 0 0 0 % R
% Ser: 0 0 0 15 0 0 0 29 15 29 0 0 43 58 15 % S
% Thr: 0 0 15 0 0 0 0 15 0 0 0 0 0 0 0 % T
% Val: 58 0 15 0 0 0 0 0 0 29 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _